| Item | Effect | Location |
| Assault Vest | Boosts Sp. Def but prevents the use of status moves. | Side Mission 71: The Burning Gaze of Watchog |
| Big Root | Increases the HP recovered from HP-draining moves. | Side Mission 49: Hit and Heal |
| Black Belt | Boosts the power of Fighting-type moves. | Side Mission 58: Better to Detect Than to Protect |
| Black Glasses | Boosts the power of Dark-type moves. | Side Mission 70: Who’s the Strongest, Huh |
| Charcoal | Boosts the power of Fire-type moves. | Side Mission 57: The Camerupt Entrepreneur |
| Dragon Fang | Boosts the power of Dragon-type moves. | Side Mission 91: Dragon You into Battle |
| Eviolite | Boosts Defense and Sp. Def if the holder can still evolve. | Side Mission 100: Starmie on High |
| Expert Belt | Slightly boosts the power of super-effective moves. | Side Mission 117: Josée’s Training |
| Fairy Feather | Boosts the power of Fairy-type moves. | Side Mission 42: A Fan of Fairy Types |
| Focus Band | May allow the holder to endure a knockout hit with 1 HP. | Side Mission 70: Who’s the Strongest, Huh |
| Focus Sash | Guarantees survival at 1 HP if hit at full health (once). | Side Mission 59: A Rematch with Hawlucha |
| Hard Stone | Boosts the power of Rock-type moves. | Side Mission 27: Restored from a Fossil |
| King’s Rock | May cause the target to flinch when inflicting damage. | Quasartico Inc., Z-A Infinite Royale Reward, Side Mission 84: Strike First to Make ‘Em Flinch |
| Leftovers | Slowly restores HP during battle. | Side Mission 68: The Best Use for Leftovers |
| Life Orb | Increases move power but damages the user slightly after each attack. | Side Mission 85: Follow Litwick |
| Light Ball | Boosts Pikachu’s Attack and Sp. Atk stats. | Side Mission 107: The World’s Greatest Pikachu |
| Lucky Egg | Grants extra experience points when held. | Side Mission 109: Wondrous Self-Healing Pokémon |
| Magnet | Boosts the power of Electric-type moves. | Side Mission 65: Apartment Block Eeriness |
| Metal Coat | Boosts the power of Steel-type moves. | Quasartico Inc., Side Mission 101: Steadfast as Steel, Side Mission 114: A Feather from Skarmory |
| Miracle Seed | Boosts the power of Grass-type moves. | Side Mission 16: The Budew Show |
| Muscle Band | Slightly boosts the power of physical moves. | Side Mission 56: We’ll Just Muscle Our Way Through |
| Mystic Water | Boosts the power of Water-type moves. | Side Mission 64: Let It Rain, Let It Pour |
| Never-Melt Ice | Boosts the power of Ice-type moves. | Side Mission 102: A Chilling Challenge |
| Normal Gem | Boosts the power of a Normal-type move once. | Side Mission 21: Spewpa in the Museum |
| Poison Barb | Boosts the power of Poison-type moves. | Side Mission 61: My Favorite Holovator |
| Power Anklet | Decreases Speed but increases Speed EV gain after battle. | Side Mission 69: A Sky Battle for Old Times’ Sake; Shop Quasartico Inc. |
| Power Band | Decreases Speed but increases Sp. Def EV gain after battle. | Side Mission 99: Pleasing Aron’s Palate; Shop Quasartico Inc. |
| Power Belt | Decreases Speed but increases Defense EV gain after battle. | Side Mission 39: Slowpoke for Slowpoke; Shop Quasartico Inc. |
| Power Bracer | Decreases Speed but increases Attack EV gain after battle. | Side Mission 38: Chasing Status; Shop Quasartico Inc. |
| Power Lens | Decreases Speed but increases Sp. Atk EV gain after battle. | Side Mission 104: Abuzz About Bug Types; Shop Quasartico Inc. |
| Power Weight | Decreases Speed but increases HP EV gain after battle. | Side Mission 72: Find My Galarian Stunfisk; Shop Quasartico Inc. |
| Quick Claw | Occasionally allows the holder to move first. | Vert District (Vert Sector 2) |
| Rocky Helmet | Damages the attacker if making direct contact. | Side Mission 92: The Beldum Blockade |
| Scope Lens | Raises the chance of landing critical hits. | Side Mission 54: Get ENERGIZED |
| Sharp Beak | Boosts the power of Flying-type moves. | Side Mission 69: A Sky Battle for Old Times’ Sake |
| Shell Bell | Restores HP when inflicting damage. | Side Mission 67: Sylveon the Soother |
| Silk Scarf | Boosts the power of Normal-type moves. | Side Mission 28: Who Says Normal Is Weak |
| SilverPowder | Boosts the power of Bug-type moves. | Side Mission 11: The Kakuna Master |
| Soft Sand | Boosts the power of Ground-type moves. | Side Mission 23: Underneath the Holovator |
| Soothe Bell | Increases the rate at which friendship grows. | Side Mission 36: Some Friendly Competition |
| Spell Tag | Boosts the power of Ghost-type moves. | Side Mission 95: A Haunting Experience |
| TwistedSpoon | Boosts the power of Psychic-type moves. | Side Mission 35: Guidance from a Yoga Master |
| Weakness Policy | Greatly boosts Attack and Sp. Atk when hit by a super-effective move. | Side Mission 86: Who Messed Up the Garden |
| White Herb | Restores lowered stats one time. | Side Mission 18: A Pan-tastic Pot of Tea |
| Wise Glasses | Slightly boosts the power of special moves. | Side Mission 21: Spewpa in the Museum |