Week 5 Fantasy Football WR Rankings and Picks feat. Amon-Ra St. Brown, Nico Collins, and more

Detroit Lions star Amon-Ra St. Brown and Houston Texans wideout Nico Collins are among the fantasy favorites heading into Week 5 of the 2025 season. Both have risen to become reliable producers on offense.

This week presents more challenging decisions that fantasy managers will have to make. Players' individual matchups play a big role in how effective they will be on the stat sheets.

Given the hurdles in fantasy football, we're here to help, and we've ranked the best wide receivers in fantasy football to ease the decision-making process for you.

Let's get right into it.

Week 5 Fantasy Football WR Rankings

Here is the ranking for Week 5:

1. Puka Nacua
2. Amon-Ra St. Brown
3. Jaxon Smith-Njigba
4. Justin Jefferson
5. Nico Collins
6. Ja'Marr Chase
7. Garrett Wilson
8. Davante Adams
9. Zay Flowers
10. Tyreek Hill
11. Emeka Egbuka
12. Deebo Samuel Sr.
13. A.J. Brown
14. George Pickens
15. Courtland Sutton
16. Xavier Worthy
17. Tetairoa McMillan
18. Quentin Johnston
19. Marvin Harrison Jr.
20. Jakobi Meyers
21. Ricky Pearsall
22. Keenan Allen
23. Jameson Williams
24. Michael Pittman Jr.
25. Chris Olave
26. Brian Thomas Jr.
27. Chris Godwin
28. Ladd McConkey
29. Jauan Jennings
30. DeVonta Smith
31. Tee Higgins
32. Jordan Addison
33. Jaylen Waddle
34. Keon Coleman
35. Stefon Diggs
36. Jerry Jeudy
37. Calvin Ridley
38. Khalil Shakir
39. Wan'Dale Robinson
40. Rashid Shaheed

Don't sleep on some of these stars who could have a big Week 5.

Week 5 Fantasy Football WR Picks

Syndication: Detroit Free Press - Source: Imagn

Amon-Ra St. Brown @CIN

Amon-Ra St. Brown is the heart of the Lions' receiving corps. While he started Week 1 slowly, he has quickly risen as a must-start commodity in fantasy football.

Week 5 presents a favorable matchup, as he'll get a chance to capitalize on the Cincinnati Bengals' 25th-ranked defense versus opposing wideouts.

Nico Collins @BAL

Houston Texans wide receiver Nico Collins will look to get on the victor's path full-time with his team. The Texans have been slipping to start the campaign, but a Week 4 shutout win against the Tennessee Titans provided some optimism.

Visiting a Baltimore Ravens team that always finds itself in high-scoring games, expect Collins to go big on Sunday against the 28th-ranked wideout defense in pro football.

Garrett Wilson vs. DAL

Jets superstar Garrett Wilson could have a big game this week. The Dallas Cowboys are the worst in the league at stopping opposing wide receivers, and Wilson is one of the NFL's most talented receivers.

Look out for some fireworks in Jersey on Sunday.