Week 12 Fantasy Football RB Rankings and Picks feat. TreVeyon Henderson, Jahmyr Gibbs, David Montgomery, Javonte Williams

The fantasy football season continues, and with the weather getting colder and harsher around the country, running backs will begin to become much more key for many teams. However, at this point, managers who didn't prioritize running backs in their drafts in August are likely to find out the hard way in the coming weeks.

Keeping this in mind, taking into account matchups, season-long production, and recent productivity, here is a look at the best fantasy football running backs in Week 12.

1. TreVeyon Henderson
2. Jahmyr Gibbs
3. Rico Dowdle
4. Bijan Robinson
5. Travis Etienne Jr.
6. Jonathan Taylor
7. Saquon Barkley
8. Christian McCaffrey
9. Kyren Williams
10. Javonte Williams
11. Derrick Henry
12. James Cook
13. Kenneth Walker III
14. Derrick Henry
15. Quinshon Judkins
16. D'Andre Swift
17. Josh Jacobs
18. Breece Hall
19. Kyle Monangai
20. Sean Tucker
21. Rachaad White
22. Aaron Jones
23. Chuba Hubbard
24. Ashton Jeanty
25. Jaylen Warren
26. Chase Brown
27. Rhamondre Stevenson
28. David Montgomery
29. Tyrone Tracy Jr.
30. Emanuel Wilson

Week 12 Fantasy Football RB Picks

TreVeyon Henderson at New York Jets v New England Patriots - NFL 2025 - Source: Getty

TreVeyon Henderson @CIN

The New England Patriots might have found their own Derrick Henry to pair with Mike Vrabel. The body type and rushing style aren't quite the same, but the productivity is. Henderson has crossed the 30-point mark twice in two games with Rhamondre Stevenson compromised.

The Cincinnati Bengals have one of the weakest defenses across the board, setting up for a monumental day for Henderson once again. The only wild card is whether Mike Vrabel is willing to unleash the rookie running back into the fourth quarter with a potential blowout on the horizon.

Sean Tucker @LAR

All season long, Sean Tucker has seen his stock rise and fall, but the back had not yet broken through. In Week 11, something clicked. With Bucky Irving stuck in purgatory between IR and playing, Tucker took 19 carries for 106 yards and two touchdowns, setting the stage for potentially another big fantasy football breakout.

However, the competition will be stiffer against the Los Angeles Rams, who have one of the better defensive lines in the NFL. Still, expect the Buccaneers to test Tucker again with Irving at risk to miss another week with foot and shoulder injuries after failing to have a single full practice in Week 11 per the Buccaneers' official injury report.

Jahmyr Gibbs vs NYG

Jahmyr Gibbs has dominated in the past month, tallying more than 35 points twice in his last four games. Gibbs dominated the Tampa Bay Buccaneers and Washington Commanders while also turning in 107 receiving yards against the Philadelphia Eagles.

This week, he faces a New York Giants team that could find itself underwater early, which would allow Gibbs to explode once again. If you have Gibbs on your fantasy football squad, you have no reason to hit the brakes on the running back.