Arizona Cardinals running back James Conner suffered a gruesome ankle injury and is slated to miss the rest of the season. This serves as a blow to many fantasy managers, but now isn't the time to panic.
One logical solution would be to target Trey Benson, who is likely to get more work this season without Conner. However, Benson has already put up nearly double-digit games every week. He likely isn't available on the waiver wire, but there are other options.
Here's a look at five running backs you can target to help fill the void left by James Conner:

#1 Cam Skattebo, New York Giants

Looking to predict NFL playoff Scenarios? Try our NFL Playoff Predictor for real-time simulations and stay ahead of the game!
Cam Skattebo dominated in 2024 with the Arizona Sun Devils, and he's now slated to be the New York Giants' top running back for the next couple of weeks. Tyrone Tracy is slated to miss multiple games due to a dislocated shoulder, per the New York Post.
If Skattebo hits, Tracy could be demoted to a backup upon his return. Skattebo's not likely to be available, but if he is, grab him ASAP. If you can get him, you might not even notice James Conner missing from your lineup.
#2 Ollie Gordon II, Miami Dolphins

Ollie Gordon II started the season third on the depth chart and has already climbed into the second slot. He isn't likely to overtake De'Von Achane, but he did see his carries skyrocket in Week 3 up to nine from one in each of the two previous games.
Gordon scored a touchdown in Week 3, which could give him even more opportunities in the future.
#3 Kyle Monangai, Chicago Bears

NFL fans are already groaning about D'Andre Swift. With the running back working through injuries, adding his backup might be wise if things take a turn for the worse. Monangai has earned at least five carries in his last two games, so the door is cracked open as a potential solid choice to help replace James Conner.
#4 Devin Singletary, New York Giants

As a short-term addition, Devin Singletary makes sense. With Tyrone Tracy out of the picture, Singletary is due to see a workload increase. However, it is unclear whether Cam Skattebo will become the team's bellcow overnight or if the team will start slowly.
Starting him should only be considered in the most desperate of situations.
#5 Justice Hill, Baltimore Ravens

With Derrick Henry suddenly going the route of Melvin Gordon in terms of fumbling the football early and often, Justice Hill could see an uptick in carries. The Baltimore Ravens are in a dangerous spot at 1-2, and are likely taking a long look in the mirror.
It's unlikely they will completely shut down Henry, but it's worth getting in front of the situation if you are looking for depth to replace James Conner.
Miami Dolphins Nation! Check out the latest Miami Dolphins Schedule and dive into the Dolphins Depth Chart for NFL Season 2024-25.