Real Betis vs Lyon Prediction and Betting Tips | November 6th 2025

Real Betis Balompie v RCD Mallorca - LaLiga EA Sports - Source: Getty
Real Betis Balompie host Lyon on Thursday

Real Betis and Lyon will battle for three points in a UEFA Europa League fixture on Thursday (November 6th). The game will be played at Estadio de La Cartuja.

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The home side are coming into the game on the back of a 3-0 victory over RCD Mallorca at the same venue in La Liga over the weekend. All three goals were scored in the first half, with Antony setting the pace with a brace while Abde Ezzalzouli completed the scoring in the 37th minute.

Lyon, meanwhile, played out a goalless draw away to Brest in Ligue 1, having played for over 82 minutes with a numerical disadvantage.

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Les Gones will shift their focus to the continent, where their last game saw them claim a 2-0 home win over Basel. Betis were held to a goalless draw away to Genk.

The stalemate left the Andalusians in 16th spot in the standings, having garnered five points from three games. Lyon are third, one of three sides to have claimed maximum points thus far.


Real Betis vs Lyon Head-to-Head and Key Numbers

  • The two sides were drawn in Group I of the 2013-14 Europa League campaign. Lyon claimed a 1-0 win at home and drew 0-0 in Spain.
  • Betis have lost just one of their last 10 games in the main stage of a European competition (four wins).
  • Lyon have not lost any of their last 12 European away games in regulation time.
  • Betis have conceded first in just one of their last 17 European games.
  • Lyon have kept a clean sheet in four of their last five games in the league phase of the Europa League.
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Real Betis vs Lyon Prediction

Real Betis have lost just one of their last nine European games at home. They are the slight pre-game favorites, and a win could see them climb into the top eight. Manuel Pellegrini's side were runners-up in the Conference League last season and are among the favorites to make a deep run in this term's Europa League.

Lyon, for their part, proved their mettle over the weekend as they held Brest to leave with a point despite being reduced to 10 men in the eighth minute.

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We expect the two sides to share the spoils in a low-scoring stalemate.

Prediction: Real Betis 1-1 Lyon


Real Betis vs Lyon Betting Tips

Tip 1 - Result: Draw

Tip 2 - Both teams to score

Tip 3 - Over 1.5 goals

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Edited by Peter P
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