Manchester United Women vs OL Lyonnes Women Prediction and Betting Tips

Manchester United Women will face OL Lyonnes Women at the The Progress With Unity Stadium on Wednesday in the penultimate round of the 2025-26 UEFA Women's Champions League's league phase. The home side marked their return to action on Sunday with a 2-1 win over West Ham United after heading into the international break in shaky form and will be keen to build on that when they resume continental action this week.

United have enjoyed a strong debut UWCL campaign, winning each of their first three outings. However, they suffered their first setback in round four, losing 5-2 to Wolfsburg Women, with a catalogue of defensive errors condemning the Red Devils to a humbling defeat in Germany.

OL Lyonnes, meanwhile, have enjoyed an outstanding start to life under head coach Jonathan Giraldez. Like their midweek hosts, they dropped points for the first time in the Champions League this season in the previous round but did so in impressive fashion, coming back from a three-goal deficit to draw 3-3 with Juventus Women.

The visitors, who sit second in the league phase with 10 points, are just one point above their midweek opponents and will be looking to widen that gap on Wednesday.

Manchester United Women vs OL Lyonnes Women Head-to-Head and Key Numbers

Wednesday's game will mark the first-ever meeting between the two teams.
United have recorded one win, one draw and one defeat in their three competitive games against French opponents.
Lyon have had 18 meetings against English opponents in European competitions. They have won 11 of those games, drawn three and lost the other four.
OL are the joint-third highest-scoring side in the Champions League this term with 11 goals.

Manchester United Women vs OL Lyonnes Prediction

The Red Devils' latest result ended a run of back-to-back defeats and they will be looking to draw inspiration from that this week. They are, however, set to host one of the tournament favorites and will need to bring their A-game if they are to secure a positive result.

Les Fenottes have recorded 12 wins and a draw in their 13 competitive outings this term and will travel to England this week in high spirits. They are comfortable favorites heading into this fixture and although they will need to guard against complacency, they should ultimately live up to that tag.

Prediction: Manchester United Women 1-2 OL Lyonnes Women