Lazio vs AC Milan Prediction and Betting Tips | December 4th 2025

Lazio will host AC Milan at the Stadio Olimpico on Thursday in the round of 16 of the 2025-26 Coppa Italia campaign. The home side will carry extra motivation into their cup opener, as they look to avenge last weekend’s 1-0 Serie A defeat to Milan.

Lazio faced Napoli at this stage of the Coppa Italia last season and secured a 3-1 victory, with Tijjani Noslin netting a brilliant hat-trick. They were, however, eliminated in the quarterfinals after a 2-0 defeat to Inter, and will be targeting a deeper run this season.

AC Milan, meanwhile, have enjoyed a strong start to life under head coach Massimiliano Allegri in the Italian’s second stint at the club. They currently sit atop the Serie A table with 28 points from 13 matches and will be aiming to carry that momentum into cup action this week.

AC Milan kicked off their Coppa Italia campaign with a 2-0 win over Bari back in August, with Rafael Leao and Christian Pulisic finding the net in either half. They then comfortably dispatched 10-man Lecce in the previous round, winning 3-0 at the San Siro with goals from three different players, including Pulisic, who scored just three minutes after coming off the bench.

---

Lazio vs AC Milan Head-to-Head and Key Numbers

• There have been 191 meetings between Lazio and Milan. The hosts have won 40 of those games while the visitors have won 85 times, with their other 66 contests ending in draws.
• The hosts have won just one of their last six games in this fixture.
• Lazio are seven-time winners of the Coppa Italia, most recently winning the domestic cup in the 2018-19 campaign. They have also finished as runners-up on three occasions.
• Milan, meanwhile, have won the Coppa Italia five times, most recently in the 2002-03 campaign. They reached the final last season but lost to Bologna, marking their 10th runners-up finish.

---

Lazio vs AC Milan Prediction

The Biancocelesti have lost two of their last three games after going unbeaten in their previous six. They are slight underdogs heading into the cup clash, but have won their last three games at the Stadio Olimpico and will fancy their chances on home turf this week.

The Rossoneri, meanwhile, are on an outstanding 13-game unbeaten streak, recording nine wins in that period. They have work to do on the road this week, but should have enough quality to take the game to penalties.

Prediction: Lazio 1-1 AC Milan

---

Lazio vs AC Milan Betting Tips

Tip 1 - Result: Draw

Tip 2 - Goals - Over/under 2.5 - Under 2.5 goals (Each of the hosts' last seven matches have produced fewer than 2.5 goals)

Tip 3 - Both teams to score: YES