Borussia Dortmund vs Bayer Leverkusen Prediction and Betting Tips | December 2nd 2025 

Borussia Dortmund and Bayer Leverkusen will trade tackles in a DFB Pokal round-of-16 tie on Tuesday (December 2nd). The game will be played at Signal Iduna Park.

The game is coming just three days after both sides faced one another in Leverkusen's home match in the Bundesliga. BVB went into the break in the lead courtesy of Aaron Anselmino's 41st-minute strike while Karim Adeyemi doubled their advantage 20 minutes into the second half. Christian Kofane halved the deficit with seven minutes left on the clock but it was not enough as the visitors left with a 2-1 win.

Leverkusen will turn their focus to the Cup and needed extra time to book their spot at this stage. A 1-1 draw away to Paderborn was followed by extra time where they triumphed 4-2. Dortmund eliminated Frankfurt 4-2 on penalties following a 1-1 away draw to get to this stage.

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Borussia Dortmund vs Bayer Leverkusen Head-to-Head and Key Numbers

• Borussia Dortmund have 48 wins from the last 109 head-to-head games. Bayer Leverkusen were victorious 34 times while 27 games ended in draws.
• Four of Dortmund's last five games across competitions have produced three goals or more.
• The last five head-to-head games have seen both sides find the back of the net.
• The away side on the day are unbeaten in the last six head-to-head games, winning four games in this run, including the last three on the bounce.
• Dortmund are unbeaten in their last seven home games across all competitions (five wins).
• Four of Leverkusen's last six competitive games have produced over 2.5 goals.

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Borussia Dortmund vs Bayer Leverkusen Prediction

A rampant Bayern Munich are running away with the Bundesliga title, with Dortmund already nine points behind the Bavarians. The DFB Pokal might represent BVB's best shot at winning silverware this season and they are likely to go all out in search of success here.

Bayer Leverkusen have overcome a tumultuous start to the season and have gotten back on track in the last few weeks. Their loss over the weekend ended their four-game winning streak across competitions, with the pick of the bunch in this run coming in their away win over Manchester City in the UEFA Champions League.

We are backing the home side to claim a narrow win with goals at both ends.

Prediction: Borussia Dortmund 2-1 Bayer Leverkusen

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Borussia Dortmund vs Bayer Leverkusen Betting Tips

Tip 1 - Borussia Dortmund to win

Tip 2 - Both teams to score

Tip 3 - Over 2.5 goals