How to defeat Osquio in Clair Obscur Expedition 33: Builds, setups, and more

You can easily defeat Osquio in Clair Obscur Expedition 33 if you know the best builds, setups, and how to use them. The newly released expansion (Verso's Draft) introduces four new bosses, with Osquio being the first you encounter. As you reach the Verso's Draft island, you will find the boss at the end of the Root of All Evil. Osquio is a two-phase boss, and unfortunately, it has no weak points to target.

This article will help you defeat Osquio in Clair Obscur Expedition 33.

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Clair Obscur Expedition 33: How to defeat Osquio

You can reach the boss's location by accessing a train from Verso's Draft that takes you in front of a portal. Once you step off, head straight into the portal and from there, make your way up the stairs at the end of the room. This will eventually take you to the Root of All Evil and directly to the boss encounter. Here are the recommended builds and characters for this fight:

Recommended builds for Verso in Clair Obscur Expedition 33 to defeat Osquio

Recommended build for Verso to defeat Osquio (Image via Kepler Interactive || YouTube/SpookyFairy)

Weapon

• Simoso

Pictos

• Second Chance
• Cheater
• Energy Master

Skils

• Powerful
• Perfect Recovery
• Perfect Break
• End Bringer
• Burden
• Marking shot

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Recommended builds for Maelle in Clair Obscur Expedition 33 to defeat Osquio

Recommended build for Maelle to defeat Osquio (Image via Kepler Interactive || YouTube/SpookyFairy)

Weapon

• Medalum

Pictos

• Protecting Attack
• Double Third
• Clea's Life

Skills

• Stendhal
• Phantom Strike
• Last Chance
• Sword Ballet
• Guard Down
• Mezzo Forte

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Recommended builds for Sciel in Clair Obscur Expedition 33 to defeat Osquio

Recommended build for Sciel to defeat Osquio (Image via Kepler Interactive || YouTube/SpookyFairy)

Weapon

• Hevason

Pictos

• Anti-Burn
• Energising Parry
• Anti-Stun

Skills

• Harvest
• Fortune's Fury
• Intervention
• All Set
• Grim Harvest
• Dark Cleansing

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How to beat Osquio in Clair Obscur Expedition 33

Initial Phase

Osquio is a two-phase boss in Clair Obscure Expedition 33; therefore, you need to beat it twice. The initial phase is not that tough, where you can use Maelle to trigger the Last Chance and then the Stendhal attack. Last Chance will reduce self-health to 1, but refills all AP, and with the Stendhal attack, the boss will lose much of its HP. Since Maelle gets two turns, she can easily regenerate her health.

Use Stendhal to deal massive damage to the boss (Image via Kepler Interactive || YouTube/SpookyFairy)

She won’t be taking hits, so her health will regenerate back to full. Meanwhile, Sciel is just there to play a support role and provide healing. You can transfer the attack to Maelle and Verso and continue the cycle to deal massive damage and successfully defeat the boss. With Verso, use the Powerful to give a buff to the other allies, increasing the damage dealt for 3 runs.

Use Verso's Powerful Skill to buff allies and increase the damage dealt for 3 runs (Image via Kepler Interactive || YouTube/SpookyFairy)

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After that, use Marking Shot to apply a mark that increases the damage dealt to the boss. Follow this up with Veto’s Perfect Break to deal light damage to Osquio. From this point onward, stick to the same approach. Apply Verso’s mark, transfer the turn using Sciel, and let Maelle handle the attacks. Sciel doesn’t need much involvement unless healing is required, making her more of a safety (Backup) option.

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Second Phase

The second phase is slightly more challenging due to the Barbapapa status effect and some of the boss's lethal attacks. If you get hit by any of his attacks, this effect reduces the damage of all your skills and attacks to just one, making it much harder to deal meaningful damage.

Fortunately, you can remove this Status Effect simply by attacking the boss using a skill. Well, in this case, use Verso's Burden to remove all Status Effects from all allies. Afterward, follow the same strategy:

• Use Sciel to give the turn to Maelle
• Use Maelle's Last Chance attack to get Verso debuff.
• Use the Stendhal Skill to defeat Osquio quickly.

Dodge the last attack to avoid taking any damage (Image via Kepler Interactive || YouTube/SpookyFairy)

During this phase, the boss uses various attacks, including Drop Kick and Pew Pew Pew. Your best bet here is to parry effectively to deflect these hits. Overall, you must properly utilize all the Skills and Parry to defeat Osquio in the DLC.

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