John Cena's remarkable WWE career is about to see the end of the road. The Cenation Leader will compete in his final match at WWE Saturday Night's Main Event, taking place on December 13, at the Capital One Arena, in Washington, D.C. The Never Seen 17 had one of the most illustrious runs in WWE history and had top rivals etched to his resume. While some of them are still active and a part of WWE, there are marquee names who are now a part of AEW. Here are the top five John Cena's biggest rivals who are currently a part of the Jacksonville-based promotion.#5. Jon MoxleyAEW's crown jewel and top star, Jon Moxley, had multiple encounters with John Cena as a member of The Shield and as a singles performer during his WWE run. Moreover, the duo has competed in highly compelling showdowns and exchanged victories. While Moxley currently reigns as a top AEW attraction, it was names like Cena who helped him set the tone for this historic tenure in Tony Khan's company.#4. Big ShowJohn Cena's first major rivalry on a grand stage came against The Big Show. The duo squared off at WrestleMania XX for the WWE United States title, which was Cena's debut at the event. He defeated The World's Largest Athlete then and had major matches with him over the years. So, it can be said that Big Show was an integral part of the rise of The Never Seen 17 in his early days.#3. Chris JerichoAt the start of his WWE career, an altercation saw John Cena slap Chris Jericho across the face during a backstage segment on SmackDown. Years later, it was Jericho who welcomed Cena to RAW, and the duo then had classic in-ring matches for the World Championship. The Ayatollah of Rock' n' Rolla was a pivotal rival in Cena's career, there at every phase, from the start through his rise to holding the prime position as WWE's Franchise Player.#2. Bryan DanielsonThe ascension of Bryan Danielson as the beloved YES! Man of WWE came at the expense of John Cena in 2013. Cena, who was the reigning WWE Champion at the time, selected Danielson as his opponent for the title at SummerSlam. The duo clashed in an epic showdown officiated by Triple H. The blockbuster encounter saw The American Dragon take out Cena with the running knee to win his first-ever WWE Championship. He then became a top attraction for the company, with his feud against Cena being crucial. #1. Adam CopelandPerhaps, one of the greatest rivals of John Cena in WWE is Adam Copeland, fka Edge. The two captivating stars began their rise to stardom around the same time. Edge cashed in his Money in the Bank on Cena to win his first WWE title in 2006. From that night on, they kick-started one of the most remarkable feuds of all time. Even for his final match, fans had constantly rallied for Cope to be his last opponent. Despite that not being a possibility, Cena and Edge will always remain one of the most historic rivalries in WWE history.